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Ship in the Panama Canal.

Panama Canal Cruises

Move through a man-made marvel, watch for rare birds and other wildlife, and take in astonishing views.

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Top Reasons to Cruise Panama Canal With Holland America

A Front-Row Seat to the Spectacular

Cruise through the jaw-dropping Panama Canal locks cocooned in comfort on a perfectly sized ship while your Cruise & Travel Director provides fascinating insights.

Sailings From East or West

Our 12- to 21-day Panama Canal cruises depart from Vancouver, Seattle, San Diego, and Ft. Lauderdale. Also new for 2025–2026 are our Panama Canal cruises sailing aboard Zuiderdam, which begin or end in Miami.

Diverse Ports of Call

Visit charming coastal towns in Mexico, El Salvador, and Costa Rica and taste the Caribbean’s vibrant flavors in Aruba and Cartagena.