NIDA Research Studies

Biased opioid agonists for treatment of opioid withdrawal in OUD: a dose-finding pilot and within-subject randomization

Currently enrolled in a methadone program?

You could qualify for a research study at NIDA.

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We are seeking study participants who are 18-75 years of age who are currently enrolled in a methadone program.
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Study Name

Biased opioid agonists for treatment of opioid withdrawal in OUD: a dose-finding pilot and within-subject randomization
Study# 20-DA-N014
Nickname: Trevena

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Purpose

Our goal is to assess the efficacy and tolerability of a biased opioid agonist for suppressing or reversing opioid withdrawal.

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Length of Study

5-29 overnight stays at the Clinical Research Unit (CRU) at Johns Hopkins Bayview campus.

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Study Activities

Taking a study drug or placebo, withdrawing from methadone for a short period before resuming the medication, questionnaires, medical assessments, blood draws, and urine samples.

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Compensation

Up to $4,631.

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Local Travel

Will be provided (via Uber Health) or reimbursed.

Complete the online pre-screener to see if you qualify for one of our studies.

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800-535-8254

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More information about this study is available here.